The association, a voluntary and non-profit organization, was established March 29, 1980, and recorded in Milan September 24, 1980.

The association aims to spread awareness of the disease in order to allow a correct diagnosis; act because in Italy you realize the full availability, and the highest levels of quality, of medicines and therapeutic aids needed to prevent and fight against the disease; support and facilitate the access of all patients to appropriate therapies; collaborate in the organization of care for patients with hereditary angioedema; create a health document identification, officially recognized with the description of the disease, therapeutic indications emergency and address of doctors turn to for more information; promote medical meetings, conferences and congresses at national and international level, to promote exchanges of information.